Total synthesis of biologically active natural products and structural analogues, molecular modelling, and discovery and development of new synthetic methods with particular interest in asymmetric reactions.
Synthesis and properties of novel and biologically important polyaza heterocycles, tandem cascade chemistry, applications of the Pummerer reaction for heterocyclic synthesis, alkaloid chemistry and the cyclization reactions of metallo carbenoids for organic synthesis.
Development of new synthetic methodology for the efficient chemical synthesis of complex molecules and the utilization of parallel (or combinatorial) synthesis techniques towards the synthesis of complex chemical libraries.