Discovery of new metal-catalyzed reactions, investigation of their mechanisms and, based on these new reactions, development of novel methodologies for synthetic organic chemistry.
Synthesis of biologically active natural products. Heterocyclic chemistry. DNA-targeted anticancer drug design. New synthetic methodology, and novel radical and cycloaddition chemistry.
Investigates design, chemical synthesis and pharmacological properties of subtype-selective GPCR ligands, TetR effectors and bioactive agents for the treatment of prion-related diseases. In German and English.