New Hampshire is part of the New England region in the northeastern United States, bounded by Vermont, Maine, Massachusetts, the Atlantic Ocean, and Canada. The state capital is Concord. Manchester and Nashua are the largest cities. The main industries are tourism, manufacturing, forestry, and some agriculture. New Hampshire was first settled by Europeans in the 1620s and made a British colony in 1741. It was the first colony to declare its independence, in 1776. It was the ninth state to ratify the US Constitution. Nowadays, New Hampshire is known for holding the first in the nation primary for Presidential candidates.