Evidence-based Medicine (EBM) is an approach that encourages the employment of the best available clinical evidence from systematic research for use in clinical practice. It seeks to augment medical traditions not yet subjected to adequate evaluation with findings based on the application of the scientific method. EBM tools include, but are not limited to, randomized controlled trials, systematic reviews (of a series of trials) and meta-analyses.
International not-for-profit organisation preparing, maintaining and promoting the accessibility of systematic reviews of the effects of health care. General information, access to the Cochrane Library, guidelines, manuals and software.
A searchable database of evidence-based answers to real-life clinical questions, with details of courses and teaching material. Developed in the Emergency Department of Manchester Royal Infirmary, United Kingdom.
Summarises current knowledge about the prevention and treatment of disease, based on appraisal of systematic reviews and randomized clinical trials. Free on-line access for physicians in the United Kingdom or in developing countries.
Search engine from NHS Evidence for health and social care professionals, providing access to evidence-based health information to assist in delivering quality patient care. Includes a Specialist Collections, along with periodic Annual Evidence Updates issued by topic area.
Initiative developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). Produces the CONSORT Statement, an evidence-based, minimum set of recommendations for reporting RCTs.
The Washington University Emergency Medicine Journal Club podcast provides an excellent way to keep up with the medical literature, improve patient care, and increase understanding of evidence-based medicine.
Features tutorials on practising and teaching this method of critical appraisal, with glossary of terms and self-evaluation questionnaire. Form the Department of Medicine at Toronto General Hospital, Canada.
Leading international not-for-profit research and development organization at the University of Adelaide, providing best available evidence to inform clinical decision-making at the point of care. With newsletter, Systematic Review Manual (SUMARI), and extensive database of systematic reviews and implementation reports.
Independent, not-for-profit organisation promoting the use of evidence in the delivery of health and disability services, active 1999 - 2012. Site contains a categorized collection of all NZGG produced evidence-based guidelines, available as PDFs for download.
Traces the foundations of evidence-based medicine to to the seminal efforts of the visionary whose call in 1971 for a collection of systematic reviews led to the creation of The Cochrane Collaboration. 
A collaboration formed to address the shortcomings of present grading systems in health care and develop a common, sensible and transparent approach to grading quality of evidence and strength of recommendations.
A growing international network for students interested in learning more about evidence-based healthcare, partnering with Cochrane UK. Includes overview of the EBM process, and a wide range of student contributions.
Online tool for the extraction and management of data for systematic review or meta-analysis, also serving as a Web-based repository of systematic review data. Joint initiative of the Agency for Healthcare Research and Quality (AHRQ) and the Evidence-based Practice Center (EPC).
This is the First "Sicily Statement" that provides an international consensus on the definition of Evidence-based Practice, the skills needed to practice EBP, and the minimum requirements for training health professionals in EBP. 
Delivers daily Patient-Oriented Evidence that Matters (DailyPOEMs) by email and produces the InfoRetriever database system of evidence-based information next to a print newsletter "Evidence-Based Practice".
A commercial evidence-based clinical decision support system for physicians at the point of care, with a differential diagnosis tool, evidence-based medical topics knowledgebase, and patient information. Now part of the Elsevier ClinicalKey service.
Critical Appraisal Skills Programme International Network is a collaboration supporting the teaching and learning of critical appraisal skills, and helping others setting up sustainable training programs via the development and dissemination of successful new teaching materials and methods.
Rare insight-rich self-directed interview of Dr. David L. Sackett, Founding Chair of The Cochrane Collaboration and pioneer in evidence-based medicine, who died May 13, 2015. From McMaster University, 103 pp. 
A non-profit initiative seeking to identify the most important gaps in the evidence for treatment efficacy, and to forge patient-clinician working partnerships to identify and prioritize unanswered questions, working closely with evidence-based affiliates. Also publishes a glossary of common evidence-based terms.
A free review tool from the Cochrane Collaboration Group used to facilitate literature reviews and the meta-analyses in accordance with the Cochrane Review Protocols. It can perform meta-analyses and present results graphically. With extensive documentation.